MicroRNAs Visit the ER

MicroRNAs Visit the ER

Little is known about where microRNAs (miRNAs) regulate their targets within the cell. In this issue, Li et al. identify a new player in the plant miRNA pathway that implicates the endoplasmic reticulum in miRNA-mediated gene silencing.

Lost in translation? microRNAs at the rough ER.

MicroRNAs (miRNAs) function to post-transcriptionally regulate target RNAs, including long non-coding RNAs and mRNAs. A recent study demonstrates that Arabidopsis miRNAs are enriched at the rough endoplasmic reticulum (ER). This enrichment is a surprise, given that most known miRNA targets are not expected to be translated at the rough ER.

mRNA expression profiles show differential regulatory effects of microRNAs between ER+ and ER- breast cancer

This peer-reviewed article was published immediately upon acceptance. It can be downloaded, printed and distributed freely for any purposes (see copyright notice below). which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Abstract Background

The Visit

flowers, gay curtains hide the marks on the windowsills where the bars used to be. I climb the stairs and go along the endless corridors with the cell-like bedrooms on one side and the open ward on the other. More visitors today, wives are going home for Bank Holiday and husbands have brought suitcases... Grandma holds up a baby to his mother: 'Hasn't he grown! You'll be home soon, Jean shuffle...

The KTH Visit in Semi-Markov Processes